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5,6-dimethyl-1,2,3-oxathiazin-4(3H)-one-2,2 dioxide

acesulfame

CAS: 33665-90-6

Molecular Formula: C4H5NO4S

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5,6-dimethyl-1,2,3-oxathiazin-4(3H)-one-2,2 dioxide - Names and Identifiers

Name acesulfame
Synonyms SUNETTE
SWEET ONE
Sunett(R)
acesulfame
Acessulfame
ACESULFAME K
RARECHEM AM UC 0205
6-methyl-1,2,3-oxathiazin-4(3h)-one2,2-dioxide
6-methyl-1,2,3-oxathiazin-4(3H)-one 2,2-dioxide
1,2,3-oxathiazin-4(3h)-one,6-methyl-,2,2-dioxide
5,6-dimethyl-1,2,3-oxathiazin-4(3H)-one-2,2 dioxide
6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-dioxide
POTASSIUM 6-METHYL-1,2,3-OXATHIAZIN-4(3H)-ONE 2,2-DIOXIDE
CAS 33665-90-6
EINECS 251-622-6
InChI InChI=1/C4H5NO4S.K/c1-3-2-4(6)5-10(7,8)9-3;/h2H,1H3,(H,5,6,7,8);/q;+1/p-1

5,6-dimethyl-1,2,3-oxathiazin-4(3H)-one-2,2 dioxide - Physico-chemical Properties

Molecular FormulaC4H5NO4S
Molar Mass163.15
Density1.83
Melting Point123-123.5°
Boling Point332.7±25.0 °C at 760 mmHg
Water Solubility270 g/L at 20 ºC
Solubility Easily soluble in water, slightly soluble in ethanol
AppearanceWhite crystalline powder
pKa-0.28±0.40(Predicted)
Storage Condition2-8℃
MDLMFCD00043833
Physical and Chemical Properties

white crystalline powder
soluble in water, slightly soluble in ethanol

UseCan be used in food, medicine and other aspects as a sweetener

5,6-dimethyl-1,2,3-oxathiazin-4(3H)-one-2,2 dioxide - Risk and Safety

WGK Germany1
RTECSRP4489165

5,6-dimethyl-1,2,3-oxathiazin-4(3H)-one-2,2 dioxide - Upstream Downstream Industry

Raw MaterialsSulfamic acid
n-Butyl acetate
Calcium hydroxide
Potassium hydroxide
Triethylamine
diketene
Molecular sieves
Dichloromethane

5,6-dimethyl-1,2,3-oxathiazin-4(3H)-one-2,2 dioxide - Reference

Reference
Show more
1. Shen Yanfei, Zhu xianna, Yao Cheng, etc. Simultaneous determination of sugars, sweeteners and preservatives in beverages by Valve-switching ion chromatography [J]. Food Science, 2018, 30 (1):31-316.
2. Yang Ban, Feng Liang, Liu Jun, Zhao Jing, Li Chao, Zhu Fagen, Shao Jianguo, Jia Xiaobin, Sun e. Study on improvement of medication compliance of pudilan antiphlogistic oral liquid for children based on material characterization technology [J]. World Chinese medicine, 2020,15(15):2221-2227.
3. Yin, Kai-Jing, et al. "Effects of different sweeteners on behavior and neurotransmitters release in mice." Journal of food science and technology 57.1 (2020): 113-121.https:// doi.org/10.1007/s13197-019-04036-6
4. [IF = 7.963] Chenzhi Hou et al."Application of multi-parameter population model based on endogenous population biomarkers and flow volume in wastewater epidemiology."Sci Total Environ. 2021 Mar;759:143480
5. [IF=3.638] Kai-Jing Yin et al."Effect and mechanism of high-fat diet on the preference for sweeteners on mice."J Sci Food Agr. 2021 Mar;101(5):1844-1853

5,6-dimethyl-1,2,3-oxathiazin-4(3H)-one-2,2 dioxide - Reference Information

sweetener the chemical name of acesulfame potassium, also known as AKsugar, white crystalline powder, easily soluble in water, slightly soluble in ethanol, stable to light and heat, and a wide range of pH values. it is one of the most stable sweeteners in the world at present. it is widely used in various foods and mainly gives the food sweetness, but it will not cause severe blood sugar reactions. In 1967, acesulfame was first discovered by the German Hearst Company. It was first approved in the UK in 1983. Its sweetness was 200 to 250 times that of sucrose. In the late 1990s, China formulated product industry standards for it. With the continuous improvement of the domestic production level, its application in the food processing industry has become wider and wider, and a larger proportion of exports.
Acesulfame has the characteristics of high sweetness, and its sweetness is about 200 times that of sucrose (3% solution); no peculiar smell, no moisture absorption, high water solubility, and good stability to heat and acid; used for food Processing will not cause microbial fermentation; safe to use, non-toxic and side effects; does not participate in metabolism, can control the intake of heat, especially suitable for obese people and blood pressure patients; does not increase the blood sugar level of the human body, especially suitable for diabetic patients.
Application in the food industry International Codex Alimentarius Commission (CAC), the European Union, the United States, Japan, Australia, New Zealand, Canada and other international organizations, countries and regions All regulations and standards allow acesulfame as a sweetener to be used in corresponding foods. For example, in some European and American countries, acesulfame can be used in beverages, candy, cakes, ice cream, jam, pudding, baked goods and table sweet bags, dairy products and other sweet products.
China's "National Food Safety Standard Food Additives Use Standard" stipulates, acesulfame can be used in ready-to-eat flavor foods with milk as the main ingredient or their prefabricated products (excluding ice cream and flavor fermented milk) (canned milk-based desserts only), frozen drinks (except edible ice), canned fruits, jams, candied fruits, Pickled vegetables, processed edible fungi and algae, canned grains, black sesame paste, canned cereals, baked goods, beverages (except packaged drinking water), jelly, table sweeteners, seasonings, soy sauce, candy, gum-based candy, etc, however, it is not allowed to be used in cold fruit products.
A variety of flakes, granules, powders and solution-like table sweeteners can be made with acesulfame. Due to its good solubility in water, acesulfame can be prepared with a high concentration of solution-like household table sweeteners. Under normal storage conditions, there is no shelf life problem of the solution. Solid and powdered table sweeteners are usually used in hot beverages. At such high temperatures, acesulfame is particularly good and stable.
when acesulfame is used alone, satisfactory sweetness can be obtained as long as the beverage contains a concentration of 800~1000mg/L or less. Because it does not contain calories and does not participate in human metabolism, it is especially suitable for diabetic patients and people who need low-energy healthy food.
use this product has a strong sweet taste, the sweetness is about 130 times that of sucrose, and its taste is similar to saccharin. There is a bitter taste at high concentrations. No moisture absorption, stable at room temperature, good mixing with sugar alcohol, sucrose, etc. As a non-nutritive sweetener, it can be widely used in various foods. According to my country's GB2760-90 regulations, it can be used for liquid, solid beverages, ice cream, cakes, jams, pickles, candied fruits, gum candy, and table sweeteners, with a maximum use of 0.3 g/kg.
It can be used as a sweetener in food, medicine, etc.
Production method It is composed of fluorosulfonyl isocyanate or chlorosulfonyl isocyanate and various active methylene compounds (including α-unsubstituted ketones, β-Diketone, β-keto acid and β-keto ester, etc.).
toxic substance data information provided by: pubchem.ncbi.nlm.nih.gov (external link)
Last Update：2024-04-09 20:13:35
5,6-dimethyl-1,2,3-oxathiazin-4(3H)-one-2,2 dioxide
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Nantong Reform Petro-Chemical CO., LTD.
Spot supply
Product Name: acesulfame Request for quotation
CAS: 33665-90-6
Tel: +86-17551318830
Email: r@reformchem.com­
Mobile: +86-17551318830
QQ: 3785839865 Click to send a QQ messageSend QQ message
Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: acesulfame Request for quotation
CAS: 33665-90-6
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: acesulfame Request for quotation
CAS: 33665-90-6
Tel: 0086-551-65418684
Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Wuhan Xingzhongcheng Chemical limited company
Spot supply
Product Name: acesulfame Request for quotation
CAS: 33665-90-6
Tel: 86+027-83389957
Email: 1024042217@qq.com
Mobile: 86+18627766980
QQ: 1024042217 Click to send a QQ message
Wechat: 18627766980
View History
5,6-dimethyl-1,2,3-oxathiazin-4(3H)-one-2,2 dioxide
Raw Materials for 5,6-dimethyl-1,2,3-oxathiazin-4(3H)-one-2,2 dioxide
Sulfamic acid
Triethylamine
Molecular sieves
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